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This page (revision-9) was last changed on 28-Dec-2012 10:20 by 1614216108

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中文名称:血清间接胆红素测定\\
英文名称:[UBil,IBIL,IB]\\
  中文名称:血清间接胆红素\\
  英文名称:[Serum bilirubin.non-glucuronidated]\\
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  血清中的胆红素大部分来源于衰老红细胞被破坏后释放出来的血红蛋白衍化而成,未在肝内经过葡萄糖醛酸化的叫做间接胆红素。\\
  当体内红细胞大量破坏,产生大量的间接胆红素,超过了肝脏代偿能力后,肝细胞不能将其全部转变为直接胆红素,因此血中间接胆红素含量升高。间接胆红素可透过细胞膜,对细胞有毒害作用,不能通过肾脏排出体外。\\
  血清中游离状态的胆红素在水溶液中溶解度低,与重氮试剂接触后不立即显色,必须加入乙醇或甲醇后才显红色,此称间接胆红素。间接胆红素随血流送至肝细胞中,经酶的作用与葡萄糖醛酸结合,生成可溶性的胆红素葡萄糖醛酸酯,再与重氮试剂作用可立即(通常在lmin内)呈红色,此称直接胆红素。两者合称总胆红素。 \\
直接胆红素又名葡萄糖醛酸胆红素、肝胆红素、胆红素钠、晶体胆红素、水溶性胆红素、胆红素B、胆红素Ⅱ、结合胆红素等。间接胆红素又名血胆红素、胶体胆红素、非水溶性胆红素、胆红素A、游离胆红素、胆红素等。\\
  生物变异\\
  生理变异:36.8%\\
  人群变异:43.2%\\
  血清中的胆红素大部分来源于衰老红细胞被破坏后释放出来的血红蛋白衍化而成,未在肝内经过葡萄糖醛酸化的叫做间接胆红素。当体内红细胞大量破坏,产生大量的间接胆红素,超过了肝脏代偿能力后,肝细胞不能将其全部转变为直接胆红素,因此血中间接胆红素含量升高。间接胆红素可透过细胞膜,对细胞有毒害作用,不能通过肾脏排出体外。
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1.7~13.7 umol/L\\
  1.7~13.7umol/L
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%%tab-医学决定水平
  无\\
/%
%%tab-危急值范围
  无\\
/%
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2.1标本应尽快分离,避免溶血,否则将影响测定结果。\\
2.2胆红素对光敏感,标准及标本均应尽量避光。\\
2.3脂血及脂溶色素对测定有干扰,应尽量取空腹血。\\
  标本应尽快分离,避免溶血,否则将影响测定结果。胆红素对光敏感,标准及标本均应尽量避光。脂血及脂溶色素对测定有干扰,应尽量取空腹血。
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  抽血前的一周内应该保持正常的生活状态,以使身体处于一个稳定的代谢水平;采血前应使受检者保持平静、松弛、避免剧烈活动,空腹十小时以上。\\
  抽血前的一周内应该保持正常的生活状态,以使身体处于一个稳定的代谢水平;采血前应使受检者保持平静、松弛、避免剧烈活动,空腹十小时以上。
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在病人安静状态下静脉采血2~3ml。\\
静脉采血:除非是卧床病人,一般取坐位采血。体位影响水分在血管内外的分布,干扰测定结果,故在采血前应静坐5min。一般自肘静脉采血,使用止血带的时间不超过1min,穿刺成功后应立即松开止血带。\\
抗凝剂选择:一般无需抗凝剂,用血清标本检测。\\
采集后注入试管中,防止剧烈震荡,并尽快送往化验室。\\
  用血清、或肝素或EDTA血浆。静脉血3-5ml,红帽、黄帽或浅绿帽真空管采血供TBIL、DBIL和肝功能组合或急诊临床化学组合测定。取血后2小时内分离血清或血浆,采集后注入试管中,防止剧烈震荡,应尽快测定,避免日光照射,溶血有干扰。
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[血液生物化学检查]\\[肝功能]
[血.生物色素]
Version Date Modified Size Author Changes ... Change note
9 28-Dec-2012 10:20 1.151 kB 1614216108 to previous
8 26-Dec-2012 14:38 1.617 kB Administrator to previous | to last Serum indirect bilirubin,IBIL,IB ==> Serum bilirubin.non-glucuronidated
7 17-Jul-2012 11:43 1.582 kB 1614216108 to previous | to last
6 17-Jul-2012 11:43 1.562 kB 1614216108 to previous | to last
5 17-Jul-2012 11:42 1.575 kB 1614216108 to previous | to last
4 07-May-2012 14:54 1.575 kB 1614216108 to previous | to last
3 23-Apr-2012 13:48 1.554 kB 1614216108 to previous | to last
2 12-Apr-2012 14:57 1.54 kB 1614216108 to previous | to last
1 10-Apr-2012 14:05 1.683 kB UnknownAuthor to last
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