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This page (revision-9) was last changed on 21-Dec-2012 14:02 by 1614216108

This page was created on 11-Apr-2012 17:08 by UnknownAuthor

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　　中文名称：血浆肝素含量测定\\
　　英文名称：heparin\\
　　中文名称：血浆肝素含量\\
　　英文名称：[Blood heparin]\\
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无。\\
　　血浆肝素含量测定是测定血液透析及抗凝治疗患者血浆中游离肝素,并动态检测抗凝治疗患者血浆中游离肝素与凝血因子的变化。血浆肝素含量的测定可以保证肝素的疗效及降低出血的危险性,且可以进行实验室监测。血浆肝素含量测定一般包括肝素辅转因子II活性测定和低分子肝素测定(LMWH)。\\
__何时检测：__\\
　　需要检查的人群：中老年人群，出现肢体疼痛、肿胀、浅静脉怒张并沿静脉可触之索条状物。
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过敏性休克、使用氮芥、放疗后、严重肝病、DIC、肝叶切除后或肝移植术后等患者血浆中可出现肝素增多。
　　过敏性休克、使用氮芥、放疗后、严重肝病、DIC、肝叶切除后或肝移植术后等患者血浆中可出现肝素增多。
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正常人为0。
凝固法：正常人为0。
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%%tab-医学决定水平
无。
/%
%%tab-危急值范围
无。
/%
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　　产色底物法。肝素可加快AT抑制因子Xa的速率。当因子Xa和AT都过量时，AT对因子Xa的抑制速率与肝素浓度成正比。残余的因子Xa活性可利用因子Xa特异性产色底物来检测，反应体系的显色强度与肝素浓度成负相关。\\
　　产色底物法：肝素可加快AT抑制因子Xa的速率。当因子Xa和AT都过量时，AT对因子Xa的抑制速率与肝素浓度成正比。残余的因子Xa活性可利用因子Xa特异性产色底物来检测，反应体系的显色强度与肝素浓度成负相关。\\
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无。\\
检查前一天不吃过于油腻、高蛋白食物，避免大量饮酒。血液中的酒精成分会直接影响检验结果。体检前一天的晚八时以后，应禁食。\\
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采血过程必须顺利，以免血小板激活释放PF4而抑制肝素活性。孵育温度和时间必须准确。重度黄疸患者应设立自身对照。检测的肝素范围有限为0-0.8U/ml。\\
标本采集：采血过程必须顺利，以免血小板激活释放PF4而抑制肝素活性。孵育温度和时间必须准确。重度黄疸患者应设立自身对照。检测的肝素范围有限为0-0.8U/ml。\\
标本运送：采集后立即送到实验室。
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[凝血活性]
Version Date Modified Size Author Changes ... Change note
9 21-Dec-2012 14:02 0.732 kB 1614216108 to previous
8 21-Dec-2012 14:00 0.762 kB Administrator to previous | to last Heparin ==> Blood heparin
7 12-Jul-2012 10:46 0.756 kB 1614216108 to previous | to last
6 12-Jul-2012 10:46 0.48 kB 1614216108 to previous | to last
5 03-May-2012 13:23 0.503 kB 1614216108 to previous | to last
4 25-Apr-2012 15:36 0.495 kB 1614216108 to previous | to last
3 24-Apr-2012 10:59 0.47 kB 1614216108 to previous | to last
2 13-Apr-2012 16:11 0.48 kB 1614216108 to previous | to last
1 11-Apr-2012 17:08 0.401 kB UnknownAuthor to last
« This page (revision-9) was last changed on 21-Dec-2012 14:02 by 1614216108