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This page (revision-16) was last changed on 21-Dec-2012 13:14 by 1614216108

This page was created on 16-Apr-2012 09:27 by UnknownAuthor

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At line 9 changed 6 lines
1. 血友病 FⅧ:C、FⅨ:C测定是诊断血友病A和B的重要指标。\\
2. 血管性血友病 1型和3型患者FⅧ:C显著减少，但不如血友病A明显、一般在20%～40%；2型患者FⅧ:C可正常。\\
3. FⅪ、FⅫ先天性缺陷 比较少见，FⅫ缺乏症患者易发生血栓栓塞性疾病。\\
4. 肝脏疾病 FⅧ:C升高。\\
5. 血液高凝状态与血栓性疾病 血浆FⅧ、FⅨ、FⅪ、FⅫ可升高。\\
　　6. 浓缩因子制剂治疗监测 血友病常常需要浓缩FⅧ因子治疗，治疗过程中可进行所输入因子的凝血活性检测。发生严重出血的血友病A患者输入浓缩FⅧ因子制剂后，FⅧ:C＞5%时，一般不会自发性出血。\\
1. 血友病\\
　　FⅧ:C、FⅨ:C测定是诊断血友病A和B的重要指标。\\
2. 血管性血友病\\
　　1型和3型患者FⅧ:C显著减少，但不如血友病A明显、一般在20%～40%；2型患者FⅧ:C可正常。\\
3. FⅪ、FⅫ先天性缺陷\\
　　比较少见，FⅫ缺乏症患者易发生血栓栓塞性疾病。\\
4. 肝脏疾病 \\
　　FⅧ:C升高。\\
5. 血液高凝状态与血栓性疾病 \\
　　血浆FⅧ、FⅨ、FⅪ、FⅫ可升高。\\
6. 浓缩因子制剂治疗监测 \\
　　血友病常常需要浓缩FⅧ因子治疗，治疗过程中可进行所输入因子的凝血活性检测。发生严重出血的血友病A患者输入浓缩FⅧ因子制剂后，FⅧ:C＞5%时，一般不会自发性出血。\\
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由于待测血浆进行了一定比例的稀释，可以避免一些异常抗凝物的干扰。但高浓度的肝素、纤维蛋白/纤维蛋白原降解产物（FDP）、自身抗体（如因子抑制物）等，仍有可能引起因子活性的假性降低。发色底物法常用于测定FⅧ:C、FⅨ:C，测定结果的影响因素比乏因子血浆纠正试验少，准确度和精密度都更高。\\
　　由于待测血浆进行了一定比例的稀释，可以避免一些异常抗凝物的干扰。但高浓度的肝素、纤维蛋白/纤维蛋白原降解产物（FDP）、自身抗体（如因子抑制物）等，仍有可能引起因子活性的假性降低。发色底物法常用于测定FⅧ:C、FⅨ:C，测定结果的影响因素比乏因子血浆纠正试验少，准确度和精密度都更高。\\
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Version Date Modified Size Author Changes ... Change note
16 21-Dec-2012 13:14 0.92 kB 1614216108 to previous
15 03-Dec-2012 10:57 0.931 kB 1614216108 to previous | to last 血浆凝血因子VIII ==> 血浆凝血因子VIII活性测定
14 03-Dec-2012 10:57 0.931 kB 1614216108 to previous | to last
13 11-Jul-2012 16:30 0.994 kB 1614216108 to previous | to last 血浆凝血因子VIII,IX,XI,XII ==> 血浆凝血因子VIII
12 11-Jul-2012 16:14 0.994 kB 1614216108 to previous | to last
11 03-May-2012 13:22 1.025 kB 1614216108 to previous | to last
10 25-Apr-2012 15:22 1.017 kB 1614216108 to previous | to last
9 24-Apr-2012 10:53 0.984 kB 1614216108 to previous | to last 血浆凝血因子VIII,XI,XII ==> 血浆凝血因子VIII,IX,XI,XII
8 24-Apr-2012 10:53 0.984 kB 1614216108 to previous | to last 血浆凝血因子VIII,,XI,XII ==> 血浆凝血因子VIII,XI,XII
7 23-Apr-2012 15:00 0.984 kB 1614216108 to previous | to last 血浆凝血因子VIIIXIXII ==> 血浆凝血因子VIII,,XI,XII
6 23-Apr-2012 15:00 0.984 kB 1614216108 to previous | to last 血浆凝血因子VIIIIXXIXII ==> 血浆凝血因子VIIIXIXII
5 20-Apr-2012 16:43 0.984 kB 1614216108 to previous | to last 血浆凝血因子VIIIXIXII ==> 血浆凝血因子VIIIIXXIXII
4 20-Apr-2012 16:42 0.984 kB 1614216108 to previous | to last 血浆凝血因子VIIIIXXIXII ==> 血浆凝血因子VIIIXIXII
3 20-Apr-2012 16:40 0.984 kB 1614216108 to previous | to last 血浆凝血因子VIII、Ⅸ、XI、XII ==> 血浆凝血因子VIIIIXXIXII
2 20-Apr-2012 16:38 0.984 kB 1614216108 to previous | to last
1 16-Apr-2012 09:27 0.95 kB UnknownAuthor to last
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