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This page (revision-7) was last changed on 24-Dec-2012 10:33 by 1614216108

This page was created on 16-Apr-2012 09:43 by UnknownAuthor

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  英文名称:α2 antiplasmin (α2-AP)\\
  英文名称:[α2 antiplasmin (α2-AP)]\\
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  1.生理变化 妊娠、分娩后和月经期,血浆α2-AP升高。\\
  2.遗传性α2-AP缺陷症 较少见,为常染色体隐性遗传,纯合子患者出血风险增加,伤口愈合差,杂合子携带者出血并发症不明显,α2-AP为35%~70%。\\
  3.获得性α2-AP缺陷症 ①肝脏疾病时,因合成减少而导致血浆α2-AP降低。②DIC和大外科手术时,由于α2-AP与PL形成纤溶酶抗纤溶酶复合物,因消耗而引起血浆α2-AP减少。③感染性疾病时,白细胞酶类可水解α2-AP,使其降低。④全身淀粉样变性患者,可因尿激酶活性增高,使α2-AP消耗增多。⑤溶栓治疗:用尿激酶、链激酶或t-PA溶栓时,大量纤溶酶原转变为纤溶酶,血浆t-PA因消耗增多而减少。\\
1.生理变化:妊娠、分娩后和月经期,血浆α2-AP升高。\\
2.遗传性α2-AP缺陷症:较少见,为常染色体隐性遗传,纯合子患者出血风险增加,伤口愈合差,杂合子携带者出血并发症不明显,α2-AP为35%~70%。\\
3.获得性α2-AP缺陷症\\
①肝脏疾病时,因合成减少而导致血浆α2-AP降低。\\
②DIC和大外科手术时,由于α2-AP与PL形成纤溶酶抗纤溶酶复合物,因消耗而引起血浆α2-AP减少。\\
③感染性疾病时,白细胞酶类可水解α2-AP,使其降低。\\
④全身淀粉样变性患者,可因尿激酶活性增高,使α2-AP消耗增多。\\
⑤溶栓治疗:用尿激酶、链激酶或t-PA溶栓时,大量纤溶酶原转变为纤溶酶,血浆t-PA因消耗增多而减少。\\
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  血浆α2-AP:A80%~120%,血浆α2-AP:Ag0.06~0.10g/L。
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%%tab-医学决定水平
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%%tab-危急值范围
/%
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  无特殊要求。
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其它凝血检验\\
  采集静脉血用109mmol/L枸橼酸钠作抗凝剂,抽血顺利,与抗凝剂充分混合。样本采集后立即送实验室。
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[纤溶活性]
Version Date Modified Size Author Changes ... Change note
7 24-Dec-2012 10:33 0.789 kB 1614216108 to previous
6 12-Jul-2012 15:36 0.795 kB 1614216108 to previous | to last
5 12-Jul-2012 15:36 0.785 kB 1614216108 to previous | to last
4 03-May-2012 13:33 0.808 kB 1614216108 to previous | to last
3 25-Apr-2012 15:28 0.8 kB 1614216108 to previous | to last
2 23-Apr-2012 11:57 0.775 kB 1614216108 to previous | to last
1 16-Apr-2012 09:43 0.706 kB UnknownAuthor to last
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