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This page (revision-8) was last changed on 14-Oct-2013 17:13 by 1614216108

This page was created on 16-Apr-2012 10:22 by UnknownAuthor

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At line 2 changed 3 lines
%%tab-血小板因子3
  中文名称:血小板因子3 \\
  英文名称:platelet factor 3,PF3\\
%%tab-血小板第3因子有效性测定(PF3)
  中文名称:血小板第3因子有效性测定(PF3) \\
  英文名称:[Platelet factor 3,PF3]\\
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  将健康人和患者富血小板血浆(PRP)和乏血小板血浆(PPP)交叉混合,以白陶土激活FⅫ,加入Ca2+后测定混合血浆的凝固时间,比较各组凝血时间的差异,从而判断PF3是否有缺陷。\\
  血小板第3因子(PF3)是血小板活化过程中形成的一种膜表面磷脂,是人体凝血的重要组成部分,是凝血因子V的固定部位,可加速凝血活酶的生成,促进凝血过程。将健康人和患者富血小板血浆(PRP)和乏血小板血浆(PPP)交叉混合,以白陶土激活FⅫ,加入Ca2+后测定混合血浆的凝固时间,比较各组凝血时间的差异,从而判断PF3是否有缺陷。\\
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  患者与健康人PRP、PPP交叉混合的凝固时间延长>5秒,视为PF3有效性降低,见于先天性PF3缺乏症、血小板无力症和尿毒症、肝硬化、原发性血小板增多症、多发性骨髓瘤、系统性红斑狼疮及一些药物的影响。\\
1.增高:见于食用饱和脂肪酸、Ⅱ型高脂血症、一过性脑缺血发作、心肌梗死、糖尿病伴血管及动脉粥样硬化等。\\
2.减低:见于先天性PF3缺乏症、血小板无力症、巨血小板综合征、血小板病、Ⅰ型糖原累积症、尿毒症、肝硬化、原发性血小板增多症、真性红细胞增多症、急性和慢性粒细胞白血病、骨髓纤维化、多发性骨髓瘤、巨球蛋白血症、系统性红斑狼疮、先天性心脏病、再生障碍性贫血、血小板减少性紫癜及恶性贫血等。
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患者与健康人PRP、PPP交叉混合的凝固时间延长<5秒。
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%%tab-医学决定水平
/%
%%tab-危急值范围
/%
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无特殊要求。
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以涂硅注射器采血3ml,注入涂硅试管中,并以109mmol/L枸橼酸钠(9:1)抗凝。
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[微血管和血小板功能]
Version Date Modified Size Author Changes ... Change note
8 14-Oct-2013 17:13 0.886 kB 1614216108 to previous
7 14-Oct-2013 17:11 0.864 kB 1614216108 to previous | to last 血小板因子3 ==> 血小板第3因子有效性测定(PF3)
6 21-Dec-2012 14:48 0.864 kB 1614216108 to previous | to last
5 12-Jul-2012 13:34 0.917 kB 1614216108 to previous | to last
4 12-Jul-2012 13:34 0.59 kB 1614216108 to previous | to last
3 03-May-2012 16:18 0.597 kB 1614216108 to previous | to last
2 23-Apr-2012 11:21 0.575 kB 1614216108 to previous | to last
1 16-Apr-2012 10:22 0.422 kB UnknownAuthor to last
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