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This page (revision-9) was last changed on 29-Jul-2013 11:06 by 1614216108

This page was created on 03-Aug-2012 13:42 by 1614216108

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　　当机体对铁的需求与供给失衡，导致体内贮存铁耗尽（iron depletion, ID），继之红细胞内铁缺乏（iron deficient erythropoiesis, IDE），最终引起缺铁性贫血（iron deficient anemia, IDA）。IDA是铁缺乏症(包括ID，IDE和IDA)的最终阶段，表现为缺铁引起的小细胞低色素性贫血及其它异常。
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1.血象：呈小细胞低色素性贫血。平均红细胞体积（MCV）低于80fl，平均红细胞血红蛋白含量（MCH）小于27pg，平均红细胞血红蛋白浓度（MCHC）小于0.32。血片中可见红细胞体小、中心浅染区扩大。网织红细胞计数多正常或轻度增高。白细胞和血小板计数可正常或减低。\\
2.骨髓象：增生活跃或明显活跃；以红系增生为主，粒系、巨核系无明显异常；红系中以中、晚幼红细胞为主，其体积小、核染色质致密、胞浆少、边缘不整齐，有血红蛋白形成不良表现（“核老浆幼”）。\\
3.铁代谢：骨髓涂片用亚铁氰化钾（普鲁士兰反应）染色后，在骨髓小粒中无深蓝色的含铁血黄素颗粒，在幼红细胞内铁小粒减少或消失，铁粒幼细胞少于0.15；血清铁蛋白降低（<12μg/L）；血清铁降低（<8.95μmol/L），总铁结合力升高（>64.44μmol/L），转铁蛋白饱和度降低（<15%）。可溶性转铁蛋白受体浓度超过8mg/L。\\
4.红细胞内卟啉代谢：FEP>0.9mmol/L（全血），ZPP>0.96mmol/L（全血），FEP/Hb（血红蛋白）>4.5mg/gHb。
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[血清转铁蛋白测定]
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[骨髓常规]\\
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[血清转铁蛋白测定]\\
[血清总铁结合力测定]\\
[可溶性转铁蛋白受体测定]\\
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[骨髓常规]
Version Date Modified Size Author Changes ... Change note
9 29-Jul-2013 11:06 1.105 kB 1614216108 to previous
8 30-Jan-2013 10:48 1.103 kB 1614216108 to previous | to last
7 29-Jan-2013 18:08 0.417 kB 1614216108 to previous | to last
6 03-Dec-2012 13:53 0.087 kB 1614216108 to previous | to last 血常规 ==> 全血细胞技术分类检测
5 03-Dec-2012 13:53 0.08 kB 1614216108 to previous | to last 红细胞内游离原卟啉测定 ==> 红细胞游离原卟啉测定
4 03-Dec-2012 11:39 0.081 kB 1614216108 to previous | to last
3 03-Aug-2012 13:44 0.06 kB 1614216108 to previous | to last
2 03-Aug-2012 13:43 0.076 kB 1614216108 to previous | to last
1 03-Aug-2012 13:42 0.06 kB 1614216108 to last
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