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This page (revision-8) was last changed on 24-Dec-2012 10:31 by 1614216108

This page was created on 16-Apr-2012 13:39 by UnknownAuthor

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　　英文名称：tissue plasminogen activator,t-PA\\
　　英文名称：[Plasminogen activator tissue type]\\
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包括组织型纤溶酶原激活物（t-PA：A）检测和抗原含量(t-PA：Ag)检测。组织纤溶酶原激活物是一种单链糖蛋白，主要由血管内皮细胞合成、分泌、不断释放入血液，广泛存在于机体的各种组织内，肝脏是组织纤溶酶原激活物灭活的主要场所。它对纤维蛋白有高度的亲和力，然后将酪氨酸纤溶酶原形成纤溶酶，降解纤维蛋白(原)和部分凝血因子，是纤溶系统的关键物质。\\
　　包括组织型纤溶酶原激活物（t-PA：A）检测和抗原含量(t-PA：Ag)检测。组织纤溶酶原激活物是一种单链糖蛋白，主要由血管内皮细胞合成、分泌、不断释放入血液，广泛存在于机体的各种组织内，肝脏是组织纤溶酶原激活物灭活的主要场所。它对纤维蛋白有高度的亲和力，然后将酪氨酸纤溶酶原形成纤溶酶，降解纤维蛋白(原)和部分凝血因子，是纤溶系统的关键物质。\\
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　　溶栓治疗监测：静脉注射t-PA 10～20分钟后，血浆t-PA：A或t-PA：Ag达到参考范围上限的2～3倍时可取得较好疗效。
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　　参考范围：血浆t-PA：A0.3～0.6活化单位/ml（发色底物法），血浆t-PA：Ag 1～12 g/L。\\
　　血浆t-PA：A0.3～0.6活化单位/ml（发色底物法），血浆t-PA：Ag 1～12 g/L。\\
　　免疫学法1~12μg/l或4.0±1.8μg/l；生物学法0.17±0.01IU/ml。（该数据来源于现代实验诊断学－检验与临床第二版，刘人伟、翁心植编）
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　　避免精神刺激和体力活动，安静10分钟后抽血。
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标本采集：3.2%枸橼酸钠0.2ml抗凝，不用压脉带准确取静脉血1.8ml，或蓝帽真空管静脉采血，3000r/min离心分离血浆。尽可能在24小时内测定。-20℃稳定3周，反复融冻不超过5次影响不大。\\
标本运送：采集后应立即送到实验室。
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[纤溶活性]
Version Date Modified Size Author Changes ... Change note
8 24-Dec-2012 10:31 0.862 kB 1614216108 to previous
7 24-Dec-2012 10:23 0.922 kB Administrator to previous | to last Tissue plasminogen activator,t-PA ==> Plasminogen activator tissue type
6 12-Jul-2012 15:25 0.888 kB 1614216108 to previous | to last
5 12-Jul-2012 15:25 0.697 kB 1614216108 to previous | to last
4 03-May-2012 13:32 0.72 kB 1614216108 to previous | to last
3 25-Apr-2012 15:26 0.712 kB 1614216108 to previous | to last
2 20-Apr-2012 16:57 0.687 kB 1614216108 to previous | to last
1 16-Apr-2012 13:39 0.611 kB UnknownAuthor to last
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