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This page (revision-12) was last changed on 16-Oct-2013 11:14 by 1614216108

This page was created on 16-Apr-2012 14:18 by UnknownAuthor

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%%tab-糖类抗原50
  中文名称:糖类抗原50\\
  英文名称:[carbohydrate antigen 50,CA50]\\
%%tab-糖链抗原CA50测定
  中文名称:糖链抗原CA50测定\\
  英文名称:[carbohydrate antigen 50]\\
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  1. CA50是胰腺和结直肠癌的标志物,因CA50广泛存在胰腺、胆囊、肝、胃、结直肠、膀胱、子宫,当细胞恶变时,由于糖基转化酶的失活或胚胎期才能活跃的某些转化酶被激活,造成细胞表面糖类结构性质改变而形成CA50,是一种普遍的肿瘤标志相关抗原,而不是特指某个器官的肿瘤标志物。CA50在多种恶性肿瘤中可检出不同的阳性率。对胰腺癌和胆囊癌的阳性检出率居首位,占94.4%;其它依次为肝癌(88%)、卵巢与子宫癌(88%)和恶性胸水(80%)等。可用于胰腺癌、胆囊癌等肿瘤的早期诊断,对肝癌、胃癌、结直肠癌及卵巢肿瘤诊断亦有较高价值。\\
  2. CA50在80%AFP阴性的肝细胞癌中呈阳性结果,作为手术治疗彻底与否的指标也有较大的准确性。另外,CA50对恶性胸水有很高的阳性检出率,而良性胸水尚无阳性报道,故CA50的检测对鉴别良、恶性胸水亦有较大的应用价值\\
  3. 萎缩性胃炎患者胃液CA50的浓度与正常人比较有显著改变。通常认为萎缩性胃炎是癌前高危期,因此CA50可作为癌前诊断指标之一。在胰腺炎、结肠炎和肺炎发病时,CA50也会升高,但随炎症消除而下降。\\
1. CA50是胰腺和结直肠癌的标志物,因CA50广泛存在胰腺、胆囊、肝、胃、结直肠、膀胱、子宫,当细胞恶变时,由于糖基转化酶的失活或胚胎期才能活跃的某些转化酶被激活,造成细胞表面糖类结构性质改变而形成CA50,是一种普遍的肿瘤标志相关抗原,而不是特指某个器官的肿瘤标志物。CA50在多种恶性肿瘤中可检出不同的阳性率。对胰腺癌和胆囊癌的阳性检出率居首位,占94.4%;其它依次为肝癌(88%)、卵巢与子宫癌(88%)和恶性胸水(80%)等。可用于胰腺癌、胆囊癌等肿瘤的早期诊断,对肝癌、胃癌、结直肠癌及卵巢肿瘤诊断亦有较高价值。\\
2. CA50在80%AFP阴性的肝细胞癌中呈阳性结果,作为手术治疗彻底与否的指标也有较大的准确性。另外,CA50对恶性胸水有很高的阳性检出率,而良性胸水尚无阳性报道,故CA50的检测对鉴别良、恶性胸水亦有较大的应用价值\\
3. 萎缩性胃炎患者胃液CA50的浓度与正常人比较有显著改变。通常认为萎缩性胃炎是癌前高危期,因此CA50可作为癌前诊断指标之一。在胰腺炎、结肠炎和肺炎发病时,CA50也会升高,但随炎症消除而下降。\\
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%%tab-医学决定水平
  无。\\
/%
%%tab-危急值范围
  无。\\
/%
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  无特殊要求。\\
  无特殊要求。
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   静脉血3ml不抗凝,或红帽或黄帽真空管采血。不用血浆,因析出纤维蛋白可致假阳性反应。溶血或血清乳浊可有影响。抗原较稳定,血清室温放置1天,4℃2周、-20℃1年测定结果在允许误差范围之内。\\
   静脉血3ml不抗凝,或红帽或黄帽真空管采血。不用血浆,因析出纤维蛋白可致假阳性反应。溶血或血清乳浊可有影响。抗原较稳定,血清室温放置1天,4℃2周、-20℃1年测定结果在允许误差范围之内。
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[血.癌抗原]
[血.肿瘤标志物检验]
Version Date Modified Size Author Changes ... Change note
12 16-Oct-2013 11:14 1.288 kB 1614216108 to previous
11 16-Oct-2013 11:14 1.28 kB 1614216108 to previous | to last 糖类抗原50 ==> 糖链抗原CA50测定
10 28-Dec-2012 17:10 1.28 kB 1614216108 to previous | to last
9 28-Dec-2012 17:09 1.352 kB 1614216108 to previous | to last 糖类抗原CA-50测定 ==> 糖类抗原50
8 05-Dec-2012 09:48 1.352 kB 1614216108 to previous | to last
7 05-Dec-2012 09:48 1.348 kB 1614216108 to previous | to last 糖类抗原50 ==> 糖类抗原CA-50测定
6 04-Dec-2012 15:16 1.348 kB 1614216108 to previous | to last
5 16-Jul-2012 16:32 1.261 kB 1614216108 to previous | to last 肿瘤标志物测定 ==> 血.肿瘤标志物
4 16-Jul-2012 16:15 1.261 kB 1614216108 to previous | to last
3 07-May-2012 15:24 1.272 kB 1614216108 to previous | to last
2 20-Apr-2012 16:11 1.248 kB 1614216108 to previous | to last
1 16-Apr-2012 14:18 1.281 kB UnknownAuthor to last
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