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This page (revision-10) was last changed on 26-Dec-2012 10:58 by 1614216108

This page was created on 17-Apr-2012 12:33 by UnknownAuthor

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　　英文名称：[growth hormone-releasing hormone，GHRH]\\
　　英文名称：[growth hormone-releasing hormone,GHRH]　or　[Somatotropin releasing hormone]\\
　　相关试验：GH及其相关因子，GH分泌的刺激和抑制试验等\\
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　　相关检查：GH及其相关因子，GH分泌的刺激和抑制试验等。\\
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　　ICT-EIA法成年男性7.3±0.5pg/ml；成年女性8.3±0.5pg/ml。\\
　　ICT-EIA法:成年男性7.3±0.5pg/ml；成年女性8.3±0.5pg/ml。\\
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%%tab-临床意义
　　GHRH是促进垂体GH合成和分泌的下丘脑激素。人GHRH由44个氨基酸残基构成，属于促胰泌素（secretin）族的脑肠肽的一种。1982年从肢端肥大症患者胰腺异位内分泌性GHRH肿瘤组织中提取和鉴定。血中半衰期约为7分钟，GHRH的N末端侧1位-29位中间部结构为其生物活性所必需，分泌后迅速从N末端降解为无活性的GHRH。除下丘脑的弓状核和正中隆起分泌外，消化管上部也有少量分泌，肝、胰、肾未见存在。\\
/%
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　　测定方法为免疫复合物转移EIA（ICT-EIA）法，灵敏度与RIA比较可提高1000倍以上。抗原识别部位为N末端从3位到中间29位立体结构两处以上。\\
　　测定方法为免疫复合物转移EIA（ICT-EIA）法，灵敏度与RIA比较可提高1000倍以上。抗原识别部位为N末端从3位到中间29位立体结构两处以上。
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　　谨从医嘱。伴随进食GHRH血浓度升高，在60-120分钟增高基础值2-3倍。影响成长激素分泌的因素，如睡眠、运动、葡萄糖负荷、胰岛素负荷以及多巴胺、溴隐亭、可乐定、精氨酸负荷等影响GH分泌的因素均无影响。可见这些因素对GH分泌的影响，不是通过GHRH途径。\\
　　谨从医嘱。
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　　采血管加EDTA-2Na和蛋白酶抑制剂最终浓度为1000Kiu/ml。迅速冷却离心分离血浆，零下20摄氏度以下冷冻保存。为避免反复融冻应分装小管保存。
　　采血管加EDTA-2Na和蛋白酶抑制剂最终浓度为1000Kiu/ml。迅速冷却离心分离血浆，-20摄氏度以下冷冻保存。为避免反复融冻应分装小管保存。
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[腺垂体分泌功能和激素]\\[临床生物化学检验]
[血.垂体功能和激素]
Version Date Modified Size Author Changes ... Change note
10 26-Dec-2012 10:58 1.104 kB 1614216108 to previous 丘脑下部垂体激素 ==> 血.垂体功能和激素
9 25-Dec-2012 15:41 1.103 kB 1614216108 to previous | to last 生长激素释放激素测定 ==> 生长激素释放激素
8 25-Dec-2012 15:41 1.103 kB 1614216108 to previous | to last
7 05-Dec-2012 17:20 1.419 kB 1614216108 to previous | to last 生长激素释放激素 ==> 生长激素释放激素测定
6 05-Dec-2012 17:20 1.419 kB 1614216108 to previous | to last
5 05-Dec-2012 17:20 1.421 kB 1614216108 to previous | to last
4 04-May-2012 09:37 1.433 kB 1614216108 to previous | to last
3 25-Apr-2012 13:47 1.427 kB 1614216108 to previous | to last
2 19-Apr-2012 16:45 1.405 kB 1614216108 to previous | to last
1 17-Apr-2012 12:33 1.159 kB UnknownAuthor to last
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