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[叶酸]\\
[维生素B12]\\
所属分类\\
[红细胞疾病]
%%tabbedSection
%%tab-概述
巨幼细胞性贫血(megaloblastieanemia,MA)是由于维生素Bu、叶酸、内因子等缺乏导致DNA合成障碍,使细胞核(主要造血细胞和胃肠道内皮细胞)发育障碍所致的一类贫血。其骨髓中粒系、红系、巨系均呈巨幼变,这种细胞未发育到成熟即在骨髓内破坏(称为无效造血),而外周血表现为大细胞性贫血并有粒细胞和血小板数减少。
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%%tab-实验室检查
__叶酸缺乏性巨幼细胞性贫血__\\
1.MCV增大,常>100fl,血涂片成熟细胞体积增大,多呈卵圆形。\\
2.白细胞和血小板数减少,中性粒细胞分叶过多(多见>4叶者)\\
3.骨髓增生活跃,红系呈典型巨幼细胞改变(>10%),粒系和巨核系细胞呈巨幼样变和核分叶过多。\\
4.血清叶酸水平<6.91nmol/L和红细胞叶酸<227nmol/L\\
__维生素B%%sub 12/% 缺乏性巨幼细胞性贫血__\\
1.MCV增大,常>100fl,血涂片成熟细胞体积增大,多呈卵圆形。\\
2.白细胞和血小板数减少,中性粒细胞分叶过多(多见>4叶者)\\
3.骨髓增生活跃,红系呈典型巨幼细胞改变(>10%),粒系和巨核系细胞呈巨幼样变和核分叶过多。\\
4.血清维生素B12水平<75pmol/L,红细胞叶酸<227nmol/L\\
5.血清甲基丙二酸水平升高\\
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%%tab-检验项目及组合列表
[异常红细胞形态检查]\\
[叶酸测定]\\
[血清维生素B12测定]\\
[血常规]
/%
/%
[血液疾病]
Version Date Modified Size Author Changes ... Change note
8 15-Oct-2013 15:27 0.688 kB 1614216108 to previous 红细胞形态检查 ==> 异常红细胞形态检查
7 29-Jul-2013 11:06 0.686 kB 1614216108 to previous | to last
6 09-Jul-2013 10:20 0.684 kB 1614216108 to previous | to last 维生素B12测定 ==> 血清维生素B12测定
5 09-Jul-2013 10:20 0.682 kB 1614216108 to previous | to last 血清维生素B12测定 ==> 维生素B12测定
4 04-Jul-2013 10:50 0.684 kB 1614216108 to previous | to last
3 05-Feb-2013 14:59 0.707 kB 1614216108 to previous | to last
2 05-Dec-2012 14:12 0.041 kB 1614216108 to previous | to last 叶酸 ==> 叶酸测定
1 05-Dec-2012 14:12 0.039 kB 1614216108 to last
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