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This page (revision-10) was last changed on 21-Dec-2012 11:47 by 1614216108

This page was created on 17-Apr-2012 14:10 by UnknownAuthor

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　　英文名称：[thrombin-antithrombin complex,AT]\\
　　英文名称：[thrombin-antithrombin complex,TAT]\\
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血浆TAT复合物增高见于90%以上DIC病例，并可用于早期DIC诊断。血栓前状态，TAT可轻度升高，提示血液有潜在的高凝性和血栓形成倾向。血栓性疾病时TAT可显著升高。溶栓治疗后，由于溶栓介导的凝血酶进一步增加，TAT进一步升高。若溶栓治疗有效，缺血的心肌成功实现再灌注，TAT可迅速下降。溶栓治疗后2小时，若TAT＜6ug/L，表明溶栓治疗成功；若溶栓治疗后36小时，TAT＞6ug/L，表明冠状动脉可能出现再栓塞。
血浆TAT复合物增高见于90%以上DIC病例，并可用于早期DIC诊断。血栓前状态，TAT可轻度升高，提示血液有潜在的高凝性和血栓形成倾向。血栓性疾病时TAT可显著升高。溶栓治疗后，由于溶栓介导的凝血酶进一步增加，TAT进一步升高。若溶栓治疗有效，缺血的心肌成功实现再灌注，TAT可迅速下降。溶栓治疗后2小时，若TAT<6ug/L，表明溶栓治疗成功；若溶栓治疗后36小时，TAT>6ug/L，表明冠状动脉可能出现再栓塞。
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凝血酶生成时，血浆中的AT能迅速与其1：1结合，生成无活性的TAT复合物，从而调节凝血反应的强度。血浆TAT浓度迅速升高，表明凝血酶浓度升高，AT被大量消耗，血液呈高凝状态，血栓形成危险性增加。因此，TAT被视为反映凝血活化的分子标志物之一。\\
　　凝血酶生成时，血浆中的AT能迅速与其1：1结合，生成无活性的TAT复合物，从而调节凝血反应的强度。血浆TAT浓度迅速升高，表明凝血酶浓度升高，AT被大量消耗，血液呈高凝状态，血栓形成危险性增加。因此，TAT被视为反映凝血活化的分子标志物之一。\\
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Version Date Modified Size Author Changes ... Change note
10 21-Dec-2012 11:47 0.787 kB 1614216108 to previous
9 28-Nov-2012 11:25 0.783 kB 1614216108 to previous | to last
8 28-Nov-2012 11:25 0.782 kB 1614216108 to previous | to last
7 28-Nov-2012 11:18 0.784 kB 1614216108 to previous | to last
6 28-Nov-2012 11:17 0.736 kB 1614216108 to previous | to last 凝血酶-抗凝血酶复合抗原 ==> 凝血酶抗凝血酶复合物测定
5 28-Nov-2012 11:11 0.736 kB 1614216108 to previous | to last
4 11-Jul-2012 11:37 0.727 kB 1614216108 to previous | to last
3 03-May-2012 13:24 0.75 kB 1614216108 to previous | to last
2 19-Apr-2012 14:37 0.717 kB 1614216108 to previous | to last
1 17-Apr-2012 14:10 0.469 kB UnknownAuthor to last
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